在斯克里普斯研究所新主編M.G.芬恩的領(lǐng)導(dǎo)下,《組合化學(xué)雜志》以ACS組合科學(xué)的名義重新發(fā)行。該雜志的特點(diǎn)是擴(kuò)大了范圍,并將建立在組合化學(xué)雜志的遺產(chǎn),在該領(lǐng)域的一個(gè)高度引用的領(lǐng)導(dǎo)者。ACS組合科學(xué)出版研究報(bào)告,描述組合、高通量和相關(guān)方法在化學(xué)、材料科學(xué)和生物學(xué)中的發(fā)展和應(yīng)用。該雜志歡迎來(lái)自廣泛科學(xué)領(lǐng)域的投稿,包括使用組合技術(shù)、分子文庫(kù)和進(jìn)化系統(tǒng)發(fā)現(xiàn)功能分子或系統(tǒng);以及加速和理解這些發(fā)現(xiàn)的工具的發(fā)展。例子包括分子合成和篩選、生物和生物啟發(fā)的分子功能發(fā)展、表現(xiàn)反饋和進(jìn)化的分子系統(tǒng)、聚合物和材料的組合合成和測(cè)試、并行操作和工程、機(jī)器人和自動(dòng)化、分析和計(jì)算方法等。ACS組合科學(xué)致力于組合和進(jìn)化分子科學(xué)代表一門(mén)新興的新學(xué)科,同時(shí)為其貢獻(xiàn)領(lǐng)域的進(jìn)一步發(fā)展提供強(qiáng)有力的工具。感興趣的范疇包括但不限于:生物活性化合物的發(fā)現(xiàn)和優(yōu)化;組合合成化學(xué);高通量,新穎的檢測(cè)和分析技術(shù);組合和高通量的新材料發(fā)現(xiàn)和優(yōu)化;蛋白質(zhì)和核酸的定向進(jìn)化;分子進(jìn)化的工具和技術(shù);利用進(jìn)化的生物系統(tǒng)和有機(jī)體來(lái)實(shí)現(xiàn)分子功能;機(jī)器人和微流體技術(shù);支持組合和高通量研究的理論和計(jì)算工具。
he Journal of Combinatorial Chemistry has been relaunched as ACS Combinatorial Science under the leadership of new Editor-in-Chief M.G. Finn of The Scripps Research Institute. The journal features an expanded scope and will build upon the legacy of the Journal of Combinatorial Chemistry, a highly cited leader in the field.ACS Combinatorial Science publishes research describing the development and use of combinatorial, high-throughput, and related methods in chemistry, materials science, and biology. The journal welcomes submissions from a broad spectrum of scientific endeavor involving the discovery of functional molecules or systems using combinatorial techniques, molecular libraries, and evolving systems; and the development of tools for speeding and understanding such discoveries.Examples include molecular synthesis and screening, biological and bio-inspired development of molecular function, molecular systems exhibiting feedback and evolution, combinatorial synthesis and testing of polymers and materials, parallel operations and engineering, robotics and automation, and analytical and computational methods, among many others.ACS Combinatorial Science is dedicated to the proposition that combinatorial and evolutionary molecular science represents an emerging new discipline, while providing powerful tools for the further development of its contributing fields. Areas of interest include but are not limited to:Discovery and optimization of biologically active compoundsCombinatorial synthetic chemistryHigh throughput and novel assays and analytical techniquesCombinatorial and high throughput discovery and optimization of new materialsDirected evolution of proteins and nucleic acidsTools and techniques for molecular evolutionUse of evolving biological systems and organisms for molecular functionRobotics and microfluidic technologiesTheoretical and computational tools supporting combinatorial and high throughput research
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