自然結(jié)構(gòu)與分子生物學(xué)是一個(gè)結(jié)構(gòu)與分子研究的綜合論壇。該雜志強(qiáng)調(diào)功能和機(jī)械的理解如何分子組成在一個(gè)生物過程中協(xié)同工作。結(jié)構(gòu)性數(shù)據(jù)或許能提供這樣的洞見,但它們不是發(fā)表在《華爾街日?qǐng)?bào)》上的先決條件。感興趣的具體領(lǐng)域包括但不限于:蛋白質(zhì)、核酸等大分子的結(jié)構(gòu)和功能多組分配合物的結(jié)構(gòu)與功能DNA復(fù)制,修復(fù)和重組染色質(zhì)結(jié)構(gòu)和重塑轉(zhuǎn)錄RNA加工翻譯轉(zhuǎn)錄和翻譯的調(diào)節(jié)非編碼rna的功能蛋白質(zhì)折疊、加工和降解蛋白質(zhì)和RNA的分類和運(yùn)輸信號(hào)轉(zhuǎn)導(dǎo)和細(xì)胞內(nèi)信號(hào)轉(zhuǎn)導(dǎo)膜過程細(xì)胞表面蛋白和細(xì)胞間的相互作用疾病的分子基礎(chǔ)
Nature Structural & Molecular Biology is an integrated forum for structural and molecular studies. The journal places a strong emphasis on functional and mechanistic understanding of how molecular components in a biological process work together. Structural data may provide such insights, but they are not a pre-requisite for publication in the journal.Specific areas of interest include, but are not limited to:Structure and function of proteins, nucleic acids and other macromoleculesStructure and function of multi-component complexesDNA replication, repair and recombinationChromatin structure and remodelingTranscriptionRNA processingTranslationRegulation of transcription and translationFunctions of noncoding RNAsProtein folding, processing and degradationSorting and trafficking of proteins and RNASignal transduction and intracellular signalingMembrane processesCell surface proteins and cell-cell interactionsMolecular basis of disease
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