與其他任何科學雜志不同，《性別差異生物學》側重于從分子到表型的生理、行為和疾病方面的性別差異，并結合了基礎研究和臨床研究。該雜志旨在提高對基本原則的理解，促進針對性別差異的治療和診斷工具的發展。這本開放獲取的雜志是備受尊敬的性別差異研究組織的官方雜志，由婦女健康研究協會聯合出版。

Unlike any other scientific journal, Biology of Sex Differences focuses on sex differences in physiology, behavior, and disease, from molecules to phenotypes, and incorporates basic and clinical research. The journal aims to improve understanding of basic principles and foster development of therapeutic and diagnostic tools that are specific for sex differences. This open access journal is the highly respected official journal of the Organization for the Study of Sex Differences, and is co-published by the Society for Women’s Health Research.